Brand Name: Fioricet

Generic Name: Acetaminophen / butalbital / caffeine

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Brand Name: Fioricet

Most Common Medical Uses
Codeine is in a class of drugs called narcotic analgesics. It relieves pain. Acetaminophen is a less potent pain reliever that increases the effects of codeine. Butalbital is in a class of drugs called barbiturates that slow down your central nervous system (brain and nerve impulses). Caffeine is believed to constrict dilated blood vessels that may contribute to tension headaches. Together, acetaminophen, butalbital, caffeine, and codeine are used to relieve complex tension headaches although precisely how it works is unknown. Acetaminophen / butalbital / caffeine / codeine may also be used for purposes other than those listed in this medication guide.

How to Take This Medication
Take acetaminophen / butalbital / caffeine / codeine exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you. Take each dose with a full glass of water. Take acetaminophen / butalbital / caffeine codeine with food or milk if it upsets your stomach. Never take more acetaminophen / butalbital / caffeine /codeine than is prescribed for you. If your pain is not being adequately treated, talk to your doctor.

Possible Side Effects
If you experience any of the following serious side effects, stop taking acetaminophen / butalbital / caffeine /codeine and seek emergency medical attention: an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives); slow, weak breathing; liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); blood problems (easy or unusual bleeding or bruising); or low blood sugar (fatigue, increased hunger or thirst, dizziness, or fainting). These side effects are very rare and are not likely to occur during proper treatment with acetaminophen and caffeine. If you experience any unusual reactions, stop taking this medicine and seek the advice of your doctor. Other, less serious side effects may be more likely to occur. Continue to take acetaminophen / butalbital / caffeine/ codeine and talk to your doctor if you experience drowsiness; dizziness,, confusion or lightheadedness; shortness of breath; dry mouth; nausea, vomiting, abdominal pain, or decreased appetite; tiredness, leg pain, or muscle weakness; agitation, irritability, nervousness, anxiety or excitability; rash or itching; feeling of intoxication; headache; or constipation.

Precautions
Use caution when driving, operating machinery, or performing other hazardous activities. Butalbital will cause drowsiness or dizziness. If you experience drowsiness or dizziness, avoid these activities. Avoid sleeping pills, antihistamines, sedatives, and tranquilizers except under the supervision of your doctor. These may also make you drowsy. Avoid alcohol. Alcohol taken during therapy with acetaminophen and butalbital can be very damaging to your liver and can increase drowsiness and dizziness. Check the acetaminophen content of other over-the-counter and prescription products while taking this medication. You should not exceed 4 grams (4000 mg) of acetaminophen per day.

Drug Interactions
Do not take acetaminophen / butalbital / caffeine / codeine if you have taken a monoamine oxidase inhibitor (MAOI) such as isocarboxazid (Marplan), phenelzine (Nardil), or tranylcypromine (Parnate) in the last 14 days. Dangerous side effects could result. The most serious interactions affecting acetaminophen / butalbital / caffeine / codeine are with those drugs that also cause sedation. The following drugs may lead to dangerous sedation if taken with acetaminophen / butalbital / caffeine / codeine: antihistamines such as brompheniramine (Dimetane, Bromfed, others), diphenhydramine (Benadryl, Nytol, Compoz, others), chlorpheniramine (Chlor-Trimeton, Teldrin, others), and others; tricyclic antidepressants, such as amitriptyline (Elavil) and doxepin (Sinequan), and serotonin reuptake inhibitors such as fluoxetine (Prozac), sertraline (Zoloft), and paroxetine (Paxil); other commonly used antidepressants, including amoxapine (Asendin), clomipramine (Anafranil), desipramine (Norpramin), imipramine (Tofranil), nortriptyline (Pamelor), and protriptyline (Vivactil); anticholinergics such as belladonna (Donnatal), clidinium (Quarzan), dicyclomine (Bentyl, Antispas), hyoscyamine (Levsin, Anaspaz), ipratropium (Atrovent), propantheline (Pro-Banthine), and scopolamine (Transderm-Scop); phenothiazines such as chlorpromazine (Thorazine), fluphenazine (Prolixin), thioridazine (Mellaril), and prochlorperazine (Compazine); and tranquilizers and sedatives such as phenobarbital (Solfoton, Luminal), amobarbital (Amytal), secobarbital (Seconal), alprazolam (Xanax), diazepam (Valium), lorazepam (Ativan), flurazepam (Prosom), and temazepam (Restoril). Do not take any of the drugs listed above without the approval of your doctor. Many other drugs contain acetaminophen, especially over-the-counter pain, fever, cold, and allergy medications. Drugs other than those listed here may also interact with acetaminophen / butalbital / caffeine / codeine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.

Missed Dose
Take the missed dose as soon as you remember. Do not take a double dose of this medication. Wait the prescribed amount of time before taking your next dose.

Storage
Store at room temperature away from moisture and heat. Keep this and all medications out of the reach of children.

Notes
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.